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Updated: Jan 6, 2026

Toxicological Assays for Testing Effects of an Epigenetic Drug on Development, Fecundity and Survivorship of Malaria Mosquitoes
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用EZH2甲基转移酶对染色体不稳定性的表观遗传调节

Yang Bai1,2,3, Albert S Agustinus2,4,5, Shira Yomtoubian1,2,3

  • 1Department of Cardiothoracic Surgery, Weill Cornell Medicine, New York, New York.

Cancer discovery
|October 2, 2025
PubMed
概括

通过EZH2进行表观遗传重编程,通过向坦基酶 (TNKS) 和CPAP,促进乳腺癌中的染色体不稳定性 (CIN). 抑制EZH2抑制CIN,为抗癌转移提供了一种新的治疗策略.

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