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Updated: Jan 16, 2026

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以HLA为重点的1型糖尿病遗传风险预测在不同祖先的人群中

Dominika A Michalek1, Courtney Tern1,2, Catherine C Robertson1,3

  • 1Department of Genome Sciences, University of Virginia, Charlottesville, VA, USA.

Diabetologia
|October 2, 2025
PubMed
概括

使用HLA区域SNP或等位基因的1型糖尿病 (T1D GRSHLA) 的遗传风险得分在各种祖先中表现相似. 跨祖先模型表现出一致的预测准确性,突出了它们更广泛应用的潜力.

关键词:
遗传风险评分是基因风险评分.哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈多个祖先的多个祖先.可转让性 可转让性1 型糖尿病 1 型糖尿病

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