患有I-III期结肠癌的患者之间的社会经济差异:检测,治疗和相对存活率
Felice N van Erning1,2, Laskarina J K Galanos1,2,3, Robin Lurvink2
1Department of Research and Development, Netherlands Comprehensive Cancer Organisation, Utrecht, The Netherlands.
International journal of cancer
|October 2, 2025
概括
社会经济地位 (SEP) 影响结肠癌的诊断和治疗. 较高的SEP与通过查和更好的治疗更早检测有关,导致轻微的生存优势.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 医疗保健服务研究 医疗服务研究
背景情况:
- 结肠癌是一个重大的公共卫生挑战.
- 社会经济地位 (SEP) 与各种结肠癌风险因素密切相关.
- 基于SEP的医疗保健获取和结果的差异令人担忧.
研究的目的:
- 研究社会经济地位 (SEP) 和结肠癌检测方法之间的关联.
- 检查SEP与结肠癌患者治疗特征之间的关系.
- 分析SEP对结肠癌存活率的影响.
主要方法:
- 利用了来自荷兰癌症登记处的数据,用于2015-2023年期间诊断出的I-III期结肠癌患者.
- 根据邮政编码级别的家庭收入评估SEP.
- 采用多变量逻辑回归和通用线性模型来分析关联.
主要成果:
- 与较低SEP患者相比,中等或较高SEP患者通过查更频繁地被诊断为SEP (31-33%vs23%).
- 较高的SEP与III期辅助化疗的增加率 (64-68%vs. 53%) 和较少的不良医院疗程 (44-47%vs. 54%) 相关.
- 原始的5年相对存活率为86.0% (较低的SEP),87.5% (中间的SEP) 和88.7% (较高的SEP).
结论:
- 中级和较高的社会经济地位与通过查更早诊断结肠癌有关.
- 在SEP较高的患者中,有利的治疗特征更常见.
- 更高的SEP给结肠癌患者带来了适度的生存优势,即使在调整其他因素后也是如此.
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