检查大麻使用和高风险新兴成年人内化症状之间的双向关联:一项前性队列研究
Jillian Halladay1,2, Kyla Belisario2,3, André McDonald2,3,4
1School of Nursing, https://ror.org/02fa3aq29McMaster University, Hamilton, ON, Canada.
Psychological medicine
|October 2, 2025
概括
这项研究发现,大麻的负面影响预示着新兴成年人内化症状增加,如抑郁和焦虑. 针对大麻使用的干预措施对于预防心理健康问题至关重要.
科学领域:
- 精神病学和心理健康 精神病学和心理健康
- 成研究 研究成研究
- 发展心理学 发展心理学
背景情况:
- 大麻使用和内化症状 (抑郁,焦虑) 经常在新兴成年人 (18-25岁) 中同时发生.
- 大麻使用和内化症状之间的双向关系的纵向证据仍然是混合的.
- 这项研究研究了大麻使用和高风险新兴成年人内化症状之间的双向纵向联系.
研究的目的:
- 调查大麻频率/后果和内化症状之间的双向纵向关系.
- 探讨大麻使用是否会影响内化症状,或者反之亦然.
- 确定影响这些关系的特定途径和人口因素.
主要方法:
- 来自961名高风险新兴成年人 (54%为女性) 的纵向数据,涉及2年的7次评估 (2018-2020年).
- 从加拿大安大略省和美国田纳西州的队列中,每隔4个月收集数据.
- 潜伏曲线模型与结构化残余分析了人与人之间的关系.
主要成果:
- 基线:较高的大麻频率/后果与较高的内化症状相关.
- 内在人:发现了显著的双向关系,特别是预测抑郁症状的负面大麻后果.
- 双向效应在女性和具有先前临床水平的内化症状的女性中更强.
结论:
- 证据支持大麻后果与新兴成年人内化症状之间的双向关系.
- 大麻的负面后果似乎预测了内化症状的增加,而不是相反.
- 对大麻使用的干预措施对于预防内化障碍至关重要,特别是对于女性和症状升高的人来说.
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