致病变体揭示了前列腺癌的候选基因,对非洲血统的男性进行生殖基因检测

Kazzem Gheybi1, Pamela X Y Soh1, Jue Jiang1

  • 1Ancestry & Health Genomics Laboratory, Charles Perkins Centre, School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Camperdown, NSW, Australia.

Nature communications
|October 2, 2025
PubMed
概括

在非洲祖先人群中进行前列腺癌 (PCa) 的生殖基因检测,揭示了DNA修复和PCa基因中的新型致病变体. 这项研究确定了更具包容性的基因查的关键候选人,解决了当前的祖先限制.

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