术后炎症和骨科手术后伤口愈合的全身酶疗法:一种随机,安慰剂和活性控制的临床研究
Ashish Suryawanshi1, Hrishikesh Patkar2, Shivaji Aute3
1Lokmanya Medical Research Centre and Hospital, Fourth-floor OPD, B Telco Road, Chinchwad, 411033, Pune, Maharashtra, India.
Scientific reports
|October 2, 2025
概括
EnMax显著减少了骨科手术后的术后疼痛和炎症,改善了恢复. 这种酶配方证明了安全性和有效性,在关键恢复标志物中表现优于安慰剂.
科学领域:
- 整形外科 整形外科 整形外科
- 药理学 药理学是指药理学的学科.
- 炎症研究 炎症研究
背景情况:
- 手术后的炎症和疼痛是骨科手术恢复的重大挑战.
- 有效的管理策略对于改善患者的治疗结果和减少并发症至关重要.
研究的目的:
- 评估EnMax片在治疗术后炎症和支持伤口愈合方面的疗效和安全性.
- 在骨科手术患者中,将EnMax与比较酶配方和安慰剂进行比较.
主要方法:
- 一个随机,双盲,安慰剂和活性控制的临床试验,涉及105名患者.
- 患者接受了EnMax,一个比较剂 (trypsin-bromelain-rutoside) 或安慰剂,并接受了标准治疗7天.
- 通过减少疼痛,炎症标志物 (CRP,ESR) 和局部刺激评估来评估有效性.
主要成果:
- 恩马克斯显著减少了疼痛 (93.10%) 和炎症 (89.77%).
- 观察到C-反应蛋白 (CRP) 显著下降57%,红细胞沉率 (ESR) 显著下降61.32%.
- EnMax在减少红疹,局部刺激,排泄和疼痛方面表现优于安慰剂和对照剂,没有报告的不良事件.
结论:
- 恩马克斯是一种安全有效的治疗选择,可以在骨科手术中增强术后恢复.
- 研究表明,与安慰剂相比,EnMax促进了更快的愈合和更好的症状管理.
- 建议进一步进行大规模的长期研究,以证实这些临床益处.
更多相关视频
04:09Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers
Published on: March 3, 2023
3.7K
03:26Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain
Published on: March 8, 2024
3.5K
相关概念视频
01:23Peripheral Artery Disease V: Postoperative Nursing Management
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
01:24Healing II: Complications
Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...