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Cholesterol Efflux Assay
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通过抑制LDLR在肝脏中的表达,ABCC4损害了血LDL胆固醇的清除

Jiaxin Chen1,2, Hui Huang2, Chi Chen2

  • 1Department of Cardiology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Communications biology
|October 2, 2025
PubMed
概括

抑制肝细胞载体ABCC4会增加低密度脂蛋白受体 (LDLR) 水平,从而提高LDL胆固醇清除率. 这一发现为高胆固醇血和动脉样硬化提供了新的治疗策略.

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