对语言的nTMS,CCEP和DCS的内部集成. 一眼看下一个未来?
Camilla Bonaudo1,2, Riccardo Carrai3, Edoardo Pieropan4,5
1Univeristy of Florence, Florence, Italy. camilla.bonaudo@unifi.it.
Acta neurochirurgica
|October 2, 2025
概括
这项研究表明,结合直接皮层刺激 (DCS),导航式跨磁刺激 (nTMS) 和皮层-皮层唤起潜能 (CCEPs),在质瘤手术期间有效地绘制语言网络.
科学领域:
- 神经外科 神经外科
- 神经科学是一个神经科学.
- 神经瘤学神经瘤学
背景情况:
- 直接皮层刺激 (DCS),导航式跨磁刺激 (nTMS) 和皮层-皮层唤起潜能 (CCEPs) 是监测大脑功能的关键技术.
- 这些方法可以协同用于绘制大脑语言网络的地图.
研究的目的:
- 介绍一个多式方法的案例研究,切除左前--岛屿低级结质瘤.
- 证明DCS,nTMS和CCEP在手术期间维护语言功能的联合实用性.
主要方法:
- 一名32岁的女性患者因左前岛内低级结质瘤而经历了清醒手术.
- 在清醒手术期间使用D080图片命名测试.
- 在手术内语言映射中使用了集成DCS,nTMS和CCEP的多式联络方法.
主要成果:
- 在前部nTMS阳性点,Penfield DCS和CCEPs刺激条之间观察到精确的对应.
- 在nTMS,DCS和CCEPs录音带的时间区域中发现了类似的匹配对应.
- 实现了高精度,nTMS,DCS和CCEPs点之间的平均距离为5.10毫米 (STD = 1.08毫米),产生100%的灵敏度,积极的预测值和精度.
结论:
- 这项研究强调了协同使用先进的神经导航和刺激技术的潜力.
- 这种多模式的方法在质瘤切除过程中有效地保护了关键的语言通路.
- 这些发现支持DCS,nTMS和CCEP的整合,以改善手术内语言映射和患者结果.
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