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对于水产养殖中益生菌应用的本土细菌菌株的表型和安全性探索

Philip Rwezawula^1,2,3, Wilson Waiswa Mwanja⁴, Juliet Roshni Mohan Raj⁵

¹Department of Animal Production and Aquatic Ecology, Faculty of Bioscience Engineering, Laboratory of Immunology and Animal Biotechnology, Ghent University, Ghent, 9000, Belgium. philip.rwezawula@ugent.be.

BMC microbiology

|October 2, 2025

概括

六种本土细菌菌株通过干扰定数感应 (QS) 信号显示出在水产养殖中作为生物控制剂的潜力. 这些菌株表现出有希望的益生菌特征,包括适应性和肠道殖民能力,支持可持续的水产养殖实践.

科学领域:

水产养殖是水产养殖的一种方式.
微生物学微生物学
益生菌益生菌益生菌

背景情况:

定数感应 (QS) 干扰是水产养殖的一个关键的抗病毒策略.
本土细菌菌株具有作为生物控制剂的潜力.
益生菌应用需要特定的体外特征才能有效.

研究的目的:

调查六种本土细菌菌株的QS干扰和益生菌潜力.
评估细菌生长,pH耐受性,盐度适应性和糖甘多样性.
在体内评估胞,抗生素易感性,生物安全性和肠道殖民.

主要方法:

对于QS干扰的N-hexanoyl homoserine乳降解试验.
在体外表征包括生长速度,pH/盐度耐受性和糖甘多样性分析.
分子化试验,抗生素敏感性查和体内斑马鱼胚胎殖民试验.

主要成果:

所有六种菌株都显示出显著的QS干扰.
菌株耐受广泛的pH (3-9) 和盐度 (1% - 4%) 范围.
四种菌株 (HSNUG,LFUG,PMUG01,PMUG02) 形成了子,对益生菌配方有益.
在体内测试证实了生物安全性和肠道殖民潜力.
益生菌适用性排名因特定特征和子形成而有所不同.

结论:

通过体外测试,可以有效地选择本地细菌菌株作为益生菌.
质量系统干扰和特定的益生菌特征对于水产养殖中的生物控制至关重要.
这项研究为开发用于可持续水产养殖的安全有效益生菌提供了基础.

关键词:

水产养殖是水产养殖的一种方式.原住民原住民的原住民莱克和甘氨酸的使用方法代谢特征代谢特征益生菌益生菌益生菌议员数量检测和火方式安全和殖民化的安全.

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