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症:在全身性红斑狼中,自身免疫性疾病活动的不常见表现

Aisha Al-Battashy¹, Houda Al Ghaithi², Batool Sh Al Lawati³

¹PGY3, Ophthalmology Residency Program, Medical Specialty Board, Muscat, Sultanate of Oman.

BMC ophthalmology

|October 2, 2025

概括

隔离性死,系统性红斑狼 (SLE) 的罕见神经眼科并发症,可能会通过皮质类固醇治疗迅速消失,这表明自身免疫原因. 这凸显了在死病例中需要考虑SLE的必要性.

科学领域:

眼科医生眼科眼科
神经学神经学
类风湿病学类风湿病学

背景情况:

系统性红斑狼 (SLE) 是一种复杂的自身免疫性疾病,临床表现各异.
神经眼科并发症,虽然很少见,可发生在SLE患者.
孤立的单边死是SLE不常见的初始表现,往往导致诊断挑战.

研究的目的:

报告一个孤立的单边死病例作为系统性红斑狼 (SLE) 的呈现征兆.
讨论诊断方面的考虑和潜在的自身免疫机制,这是这种罕见的神经眼科症状的基础.
强调在疑似SLE爆发时及时免疫抑制治疗的重要性.

主要方法:

一个病例报告,一个30岁的女性有SLE病史,呈现急性单边死.
诊断工作包括大脑和轨道MRI,以及针对SLE活动的血清学测试.
进行了结构原因的排除和SLE疾病活性评估.

主要成果:

患者呈现急性右侧死,没有其他神经缺陷.
调查排除了结构性原因,血清学测试表明中度活跃的SLE.
在高剂量全身皮质类固醇给药后的24小时内,症完全消失.

结论:

孤立的单边死可能是SLE的罕见神经眼科表现.
对皮质类固醇的快速反应表明炎症或自身免疫病因.
对于疑似与SLE相关的神经眼科事件,应考虑立即免疫抑制治疗.

关键词:

上腺皮层荷尔蒙上腺皮层荷尔蒙自身免疫性疾病是一种自身免疫性疾病.红斑狼,全身性红斑狼神经眼科神经眼科症 (Ptosis) 是一种致死症.

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