客观测量失眠患者的认知功能,有或没有并发性抑郁症,治疗失眠的认知行为疗法
Sandra Tamm1, Susanna Jernelöv2,3, Erik Forsell2
1Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden. sandra.tamm@ki.se.
BMC psychiatry
|October 2, 2025
概括
失眠的认知行为疗法 (CBT-I) 显示出改善失眠患者的客观认知功能的潜力,即使是那些患有并发性抑郁症的人. 虽然两组之间的差异很小,但CBT-I对注意力和情绪处理产生了积极的影响.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 临床医学 临床医学
背景情况:
- 失眠和抑郁症经常同时发生,导致认知障碍.
- 对于失眠的认知行为疗法 (CBT-I) 已知可以改善主观认知,但其对客观认知表现的影响尚不清楚.
- 这项研究调查了有或没有伴随性抑郁症的失眠患者的认知功能,并评估了CBT-I后的变化.
研究的目的:
- 为了比较失眠患者和伴随失眠和抑郁症患者之间的认知表现.
- 评估互联网提供的失眠认知行为疗法 (CBT-I) 对客观认知结果的影响.
- 确定受共同抑郁症和CBT-I影响的特定认知领域.
主要方法:
- 对通过互联网提供CBT-I的两个随机临床试验中170名参与者的数据 (124人进行纵向分析) 的分析.
- 使用CANTAB计算机化测试电池进行认知性能评估.治疗前后.
- 应用线性回归和混合效应模型来分析认知结果.
主要成果:
- 在17个结局中的7个结局中,观察到客观认知表现的显著改善,包括视觉处理,执行功能和情绪处理.
- 伴随性抑郁症与空间工作记忆 (Spatial Span任务) 的受损有关,但并没有显著影响大多数其他认知任务.
- 在治疗后失眠或抑郁症严重程度的变化与认知表现的变化之间没有发现显著的相关性.
结论:
- 失眠患者和伴随性抑郁症患者之间的认知表现差异很小.
- CBT-I可能会在注意力,工作记忆,执行功能和情绪处理领域中增强客观认知功能.
- 建议进行进一步的研究,以控制实践效应,并调查CBT-I的长期认知影响.
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