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Updated: Jan 16, 2026

Describing a Transcription Factor Dependent Regulation of the MicroRNA Transcriptome
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在瘤细胞表达的VISTA受m6A的调节,并通过NSCLC的STAT3/CCL22影响免疫微环境

Hao Xu1,2, Kaikai Shen3, Bei Jiang4

  • 1Department of Respiratory and Critical Care Medicine, Jinling Hospital, Nanjing Medical University, Nanjing, China.

Journal of translational medicine
|October 2, 2025
PubMed
概括

在非小细胞肺癌细胞上的V-域免疫球蛋白抑制T细胞激活 (VISTA) 表达受到m6A修饰的调节. 这增强了CD8+ T细胞的反应,减少了免疫抑制,提供了一个新的免疫治疗点.

关键词:
CCL2222 这是一本书.免疫治疗是一种免疫疗法.在METTL3中,METTL3是METTL3的第一个类型.在NSCLCLC中,我们可以看到.在STAT3中,我们可以使用STAT3.在视野中看到的.在 YTHDF1 的位置上.m6A 修改的修改

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