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Updated: Jan 16, 2026

Interview: HIV-1 Proviral DNA Excision Using an Evolved Recombinase
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Published on: June 16, 2008

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在HIV-1感染中,有缺陷的前病毒会通过促进体外接收引起T细胞重编程

Martin V Hamann, Lisa Brauckmann, Christoph Schwarz

    bioRxiv : the preprint server for biology
    |October 3, 2025
    PubMed
    概括

    艾滋病毒前病毒可以通过劫持宿主基因来重新编程CD4+T细胞,从而导致免疫逃避和持久性. 阻止前病毒转录可能有助于减轻艾滋病毒感染者 (PLWH) 接受抗逆转录病毒疗法 (ART) 的这些影响.

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