需要Wnt共受体Arrow-LRP5/6才能在Drosophila中建立平面细胞极性

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Updated: Jan 6, 2026

Modeling Paracrine Noncanonical Wnt Signaling In Vitro
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Modeling Paracrine Noncanonical Wnt Signaling In Vitro

Published on: December 10, 2021

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Ursula Weber, Reza Farhadifar, Marek Mlodzik

    bioRxiv : the preprint server for biology
    |October 3, 2025
    PubMed
    概括

    箭头 (Arr) /LRP5/6对于Wnt/平面细胞极性 (PCP) 信号传输至关重要,与当前的模型相反. 失去Arr会导致PCP缺陷,这表明它在发育和组织平衡中起着至关重要的作用.

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