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Updated: Jan 16, 2026

Assay to Measure Nucleocytoplasmic Transport in Real Time within Motor Neuron-like NSC-34 Cells
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正常和ALS C9orf72运动神经元成熟期间染色体和核结构的动态变化

Özgün Uyan1, Snehal Sambare2, Marlies E Oomen2

  • 1Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.

bioRxiv : the preprint server for biology
|October 3, 2025
PubMed
概括

神经成熟涉及基因表达和染色体组织的重大变化. 这些过程在患者的运动神经元中受损C9orf72相关的肌缩侧面硬化症 (ALS).

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