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Updated: Jan 16, 2026

Programming Stem Cells for Therapeutic Angiogenesis Using Biodegradable Polymeric Nanoparticles
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非整合性直接重编程产生治疗性内皮细胞,具有持续的血管再生能力,通过纳米矩阵输送得到增强

Sangho Lee, Dandan Chen, Yoshiaki Tanaka

    bioRxiv : the preprint server for biology
    |October 3, 2025
    PubMed
    概括

    使用腺病毒ETV2 (Ad-ETV2) 将纤维细胞直接重新编程为内皮细胞 (rEC),为血管再生提供了临床解决方案. 用氨基 (PA) -RGDS封装可增强长期细胞移植和在缺血条件下治疗疗效.

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