阻塞性睡眠呼吸暂停和男性生殖功能之间的关联:一个横截面研究与分层分析
Wei Zhang1, Xu Wu2,3, Yuyang Zhang4
1Department of Urology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Frontiers in endocrinology
|October 3, 2025
概括
阻塞性睡眠呼吸暂停 (OSA) 与男性的精子质量和丸激素降低有关. 早期的OSA查对男性生殖健康至关重要.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 睡眠医学 睡眠医学
- 安德罗学与人类学
背景情况:
- 阻塞性睡眠呼吸暂停症候群 (OSAHS) 是一种影响系统生理学的普遍睡眠障碍.
- 新出现的证据表明OSA和男性生殖健康之间存在联系,但这种联系需要进一步描述.
研究的目的:
- 为了研究OSA,精液质量和生殖年龄男性的性激素概况之间的关系.
主要方法:
- 108名新诊断的OSA患者 (年龄在20-40岁) 和84名健康对照人接受了多睡眠图 (PSG),体检,精液分析和性激素检测.
- OSA的严重程度是根据PSG的呼吸暂停-呼吸暂停指数 (AHI) 来确定的.
主要成果:
- 与对照组相比,OSA患者的体重和BMI更高,精子度,总运动率,渐进运动率和水平明显降低 (p <0.01).
- 增加的OSA严重程度与降低的精液参数和氧和度相关.
- 多变量分析显示,AHI与精子度降低,总运动率和渐进运动率 (p < 0.001) 独立相关.
结论:
- 在生殖年龄的男性中,OSA独立地与精液质量受损和丸激素水平降低有关.
- 这些发现强调了未经治疗的OSA对生殖的潜在影响,并强调了早期查和干预的必要性.
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