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测量学习裂口修复的最佳模拟器复杂性:成本效益分析

Krystof Stanek1,2,3, Michael Silver4, Andrew Edman4

  • 1From the Department of Plastic and Oral Surgery, Boston Children's Hospital, Boston, MA.

Plastic and reconstructive surgery. Global open
|October 3, 2025
PubMed
概括

一个新的,复杂性较低的裂唇模拟器与外科实习生的高保真版本一样有效. 这种具有成本效益的模拟可以增加对裂口修复手术教育的机会.

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This lesson introduces two critical methods in pharmacokinetics, the Wagner-Nelson and Loo-Riegelman methods, used for estimating the absorption rate constant (ka) for drugs administered via non-intravenous routes. The Wagner-Nelson method relates ka to the plasma concentration derived from the slope of a semilog percent unabsorbed time plot. However, it is limited to drugs with one-compartment kinetics and can be impacted by factors like gastrointestinal motility or enzymatic degradation.
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