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Updated: Jan 16, 2026

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以EZH2为媒介的H3K27me3将微生物内素损失与抑郁症联系起来:肠-大脑表观遗传开关

Sen Zhu1, Xuan Li2, Ying Yu3

  • 1Department of Obstetrics, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430071, China.

Theranostics
|October 3, 2025
PubMed
概括

肠道微生物群的不平衡通过耗尽因素,从而提高EZH2.2,导致抑郁症. 这种表观遗传调节器使关键基因沉默,导致抑郁行为. 用酸准EZH2为这些疾病提供了一种新的治疗方法.

关键词:
在 EZH2 中使用.H3K27me3 在线阅读库马里酸是一种酸.抑郁 抑郁症 抑郁症 抑郁症 是一种肠道微生物 肠道微生物

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