患有心力衰竭的患者睡眠呼吸暂停的患病率和特征:单中心研究
Bayyaram Rambhoopal Reddy1, Jeetendra Kumar Patra1, Manoranjan Pattnaik1
1Department of Pulmonary Medicine, Srirama Chandra Bhanja (SCB) Medical College and Hospital, Cuttack, IND.
Cureus
|October 3, 2025
概括
这项研究发现,86%的稳定心力衰竭患者有睡眠呼吸暂停,最常见的是阻塞性睡眠呼吸暂停 (OSA). 提高对心力衰竭患者睡眠呼吸暂停的认识和查对于更好的管理至关重要.
科学领域:
- 心脏病学 心脏病学
- 肺部医学 肺部医学
- 睡眠医学 睡眠医学
背景情况:
- 心力衰竭 (HF) 是一种慢性心血管疾病,预后不佳.
- 睡眠呼吸暂停是HF患者经常出现的并发症,增加死亡风险.
- 阻塞性睡眠呼吸暂停 (OSA) 与保持喷射分数的高关联,而中央睡眠暂停 (CSA) 与高严重程度相关.
研究的目的:
- 为了确定睡眠呼吸暂停在稳定的心力衰竭患者的患病率.
- 在HF患者的睡眠呼吸暂停的特征.
- 为了检查睡眠呼吸暂停和HF严重程度和症状之间的关联.
主要方法:
- 一个单中心的横截面研究,涉及50名稳定的HF患者.
- 患者接受了夜间多睡眠学,以诊断和评估睡眠呼吸暂停.
- 排除标准包括NYHA IV类,休息期缺氧,最近的心脏事件和其他并发症.
主要成果:
- 86%的HF患者有睡眠呼吸暂停,其中68%的OSA和18%的CSA.
- 与男性 (82.75%) 相比,女性患者的睡眠呼吸暂停患病率更高 (90.5%).
- 呼吸暂停-呼吸暂停指数 (AHI) 与睡眠期间氧和度降低相关,但BMI,LVEF,年龄和性别不是睡眠暂停严重程度的独立风险因素.
结论:
- 在稳定的心力衰竭患者中,睡眠呼吸暂停,特别是OSA的患病率很高.
- 睡眠呼吸暂停发生在所有HF类别中,女性的流行率显著.
- 这些发现强调了需要加强对HF人群睡眠呼吸暂停的查和管理.
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