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Updated: Jan 16, 2026

Single Particle Cryo-Electron Microscopy: From Sample to Structure
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Single Particle Cryo-Electron Microscopy: From Sample to Structure

Published on: May 29, 2021

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验证3D冷EM单颗粒重建的正确性和手性,使用Ewald的球体校正

R Bromberg, Y Guo, D Borek

    Structural dynamics (Melville, N.Y.)
    |October 3, 2025
    PubMed
    概括

    这项研究引入了一种新的方法,用于在电子显微镜中分离量子散射贡献. 这种方法可以自动确定手性,并提高3D重建的质量.

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    相关概念视频

    Electron Microscope Tomography and Single-particle Reconstruction01:07

    Electron Microscope Tomography and Single-particle Reconstruction

    Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
    Electron Tomography
    Electron tomography can be performed either in TEM or STEM (scanning transmission...
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