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Updated: Jan 16, 2026

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谷氨胺代谢和氨死亡:针对性调节以增强癌症免疫疗法

Fei Du1,2, Linlin Xiao1, Wang Guojun1

  • 1Department of Pharmacy, The Fourth Affiliated Hospital of Southwest Medical University, Meishan, Sichuan, China.

Frontiers in immunology
|October 3, 2025
PubMed
概括

氨在T细胞中的积累可以触发一种新的细胞死亡途径,增强抗瘤免疫力. 针对这种"氨死亡"可能会改善癌症免疫疗法对目前治疗耐药的患者的结果.

关键词:
在 CD8+ T 细胞中.氨是死亡的氨.谷氨胺是一种胺.免疫疗法 免疫疗法瘤微环境是一个微环境.

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