胎盘体重和形态与出生时低体重的关联:一个病例控制研究
Jing Liu1, Die Liu1, Haixiao Liang1
1Department of Pediatrics, China-Japan Friendship Hospital, Beijing, China.
Open medicine (Warsaw, Poland)
|October 3, 2025
概括
胎盘的重量和宽度与期内低出生体重 (TLBW) 有显著的关联. 胎盘尺寸较小增加了TLBW的风险,突出了胎盘在胎儿发育中的关键作用.
科学领域:
- 产科和妇科 产科和妇科
- 新生儿健康 新生儿健康
- 围产儿医学 围产儿医学
背景情况:
- 有限的研究存在于胎盘在确定出生体重的作用.
- 调查胎盘形态与期内低出生体重 (TLBW) 之间的相关性至关重要.
研究的目的:
- 探索胎盘体重,形态和短期低出生体重 (TLBW) 的发生率之间的联系.
主要方法:
- 一项涉及290名新生儿的病例控制研究 (115名TLBW,175名对照) 从2018年1月到2022年11月.
- 根据出生日期,妊娠年龄,性别和母亲年龄对应的对照.
- 后勤回归分析被用来构建一个包含胎盘参数的预测模型.
主要成果:
- 与对照组相比,患有TLBW的新生儿的胎盘重量,长度,宽度和厚度明显较低 (P < 0.001).
- 在多变量分析中,胎盘重量和宽度被确定为TLBW的独立预测因素.
- 胎盘体重和宽度低于50百分位,与TLBW风险增加密切相关.
结论:
- 胎盘重量和宽度是与短期低出生体重 (TLBW) 相关的关键指标.
- 对胎盘功能,组织学和病理生理学的进一步研究是有必要的,以阐明胎儿生长限制的机制.
相关概念视频
Teratogenicity
4.0K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
4.0K
Pathophysiology of Diabetes
3.1K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
3.1K


