一个FHIR规范以正式化队列定义
Britta Berens1, Joscha Grüger2,3, Carolin Poschen1
1Department of Computer Science, Trier University of Applied Sciences, Trier, Germany.
Studies in health technology and informatics
|October 3, 2025
概括
本研究引入了一个框架,用于使用FHIR资源标准化回顾性研究队列定义. 这提高了医疗研究临床数据的可复制性和自动重复使用.
科学领域:
- 医疗信息学 医疗信息学
- 临床研究方法论 临床研究方法论
背景情况:
- 追溯研究对医学研究至关重要.
- 队列定义通常是无结构的,阻碍了可重现性和数据重用.
- 缺乏标准化限制了临床数据的自动处理.
研究的目的:
- 提出一个框架,用于结构化和标准化对队列定义的规范.
- 提高队列数据的可复制性,一致性和自动重复使用.
- 为了支持基于FHIR (快速医疗互操作性资源) 的队列定义.
主要方法:
- 对回顾性研究的系统审查,以导出建模类别.
- 开发一个使用六个类别的框架:人口统计,术语,临床结果,时间数据,时间关系和逻辑组合.
- 使用原生或最小扩展的FHIR属性实现.
主要成果:
- 一个框架,在FHIR资源中实现结构化和标准化的队列定义.
- 队列定义和临床数据之间的一对一对应.
- 实现了人类可读性和对队列数据的自动处理.
结论:
- 拟议的基于FHIR的框架解决了对回顾性研究中标准化队列定义的需求.
- 促进使用案例的自动处理,如可行性搜索和透明文档.
- 提高临床数据在研究中的可靠性和可重复使用性.
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