人工智能驱动的临床决策支持,以减少医院获得的静脉血栓栓塞:试验协议
Colin G Walsh1,2,3, Yufei Long1, Laurie Lovett Novak1
1Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee.
JAMA network open
|October 3, 2025
概括
这项研究将评估人工智能 (AI) 驱动的临床决策支持是否可以减少医院获得的静脉血栓塞栓症 (HA-VTE),而不会增加不良事件. 该试验将将人工智能驱动的警报与城市和农村医院的标准护理进行比较.
科学领域:
- 医疗信息学 医疗信息学
- 临床试验 临床试验
- 医疗保健服务研究 医疗服务研究
背景情况:
- 医院获得的静脉血栓塞栓症 (HA-VTE) 是美国医院可预防死亡的一个重要原因.
- 目前的HA-VTE风险模型在指导预防决策方面缺乏经过证明的有效性.
- 现有的风险评估工具在各种医疗保健环境中的通用性仍然不确定.
研究的目的:
- 评估人工智能 (AI) 驱动的临床决策支持 (CDS) 在减少住院成年人中HA-VTE发病率方面的有效性.
- 评估人工智能驱动的CDS在城市和农村医院环境中的影响.
- 为了确定人工智能驱动的CDS是否可以减少HA-VTE而不会增加出血等不良事件.
主要方法:
- 一项实用,随机的临床试验,涉及城市和农村医院的风险VTE的成年患者.
- 患者将被随机分配1:1接受人工智能驱动的CDS警报或标准风险评估.
- 主要结果是HA-VTE的发病率,次要结果包括停留时间,再接收和安全事件.
主要成果:
- 本节不适用,因为该研究是前性的.
结论:
- 这项试验将为AI驱动的CDS在预防HA-VTE的有效性提供关键的见解.
- 调查结果将为在各种医疗保健环境中实施人工智能工具提供信息,解决城乡差异.
- 这项研究旨在确定人工智能是否可以通过减少由HA-VTE引起的可预防死亡来提高患者安全.
相关概念视频
Venous Thrombosis III: Interprofessional Care
254
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
254
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
262
The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
262
Venous Thrombosis IV: Nursing Management
175
Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
175
Venous Thrombosis I: Introduction
245
Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
245
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
267
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
267
Clinical Trials: Overview
4.5K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
4.5K


