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单剂量口服流感抗病毒原药,通过胆固醇结合激活

Chenning Li1,2, Xun Lv2,3, Chenxi Cheng1,4

  • 1Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.

Journal of medicinal chemistry
|October 3, 2025
PubMed
概括

一种新型的胆固醇结合的奥塞尔塔米维尔碳酸盐原药在小鼠中提供了长时间的全身暴露和单剂量流感保护. 这一进步解决了当前奥塞塔米维尔治疗的频繁剂量限制.

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