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Updated: Jan 6, 2026

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起的明星:GLP-1受体多态性对利拉格卢提德的反应的影响

Mona Mashayekhi1,2, Bilgunay Ilkin Safa1, Hui Nian3

  • 1Vanderbilt University Medical Center, Department of Medicine, Division of Diabetes, Endocrinology and Metabolism, Nashville, Tennessee, USA.

The Journal of endocrinology
|October 3, 2025
PubMed
概括

GLP-1R rs6923761变体增强了利拉格卢提德的减肥效果,但减少了肥胖症的代谢效益. 这一遗传因素对治疗结果产生双重影响,影响体重和代谢标志物.

关键词:
在GLP-1受体.PAI-1是PAI-1的第一个类型.利拉格卢提德 (liraglutide) 是一种葡萄糖类药物.需要使用的是RS6923761减肥 减肥 减肥 减肥 减肥 减肥

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