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Updated: Jan 16, 2026

Identification and Classification of Position-specific GABAA Receptor Subunit Missense Variants for Their Role In Hippocampal Pyramidal Neurons
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Identification and Classification of Position-specific GABAA Receptor Subunit Missense Variants for Their Role In Hippocampal Pyramidal Neurons

Published on: June 6, 2025

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一个单个样本特定基因组合效应的多层编码器预测模型 (MLEC-iGeneCombo).

Yun Shen1, Kunjie Fan1, Birkan Gökbağ1

  • 1Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America.

PLoS computational biology
|October 3, 2025
PubMed
概括

合成致死性 (SL) 基因对的预测差异很大. 一种新的基因组合效应 (GCE) 测量和深度学习模型 (MLEC-iGeneCombo) 为基因淘汰实验提供一致的GCE预测.

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