轮班工作与结石事件的关联中的生活方式因素
Man He1, Xiuping Dou1, Yang Su1
1Department of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
Mayo Clinic proceedings
|October 3, 2025
概括
轮班工作增加了结石的风险,特别是在年轻人和非人工劳动者身上. 健康的生活方式部分调解了这一关联,强调了有针对性的健康促进的必要性.
科学领域:
- 职业健康 职业健康 职业健康
- 腎臟病學 (nephrology) 是一種醫學專業.
- 流行病学 流行病学
背景情况:
- 轮班工作在全球普遍存在,并与各种不良健康结果有关.
- 结石是一种常见且经常复发的疾病,具有多因素的病因.
- 轮班工作对结石发病率的具体影响和生活方式因素的作用仍然不完全理解.
研究的目的:
- 调查轮班工作 (类型,频率,持续时间) 与结石事件之间的关联.
- 检查生活方式因素在轮班工作和结石之间关系中的潜在调解作用.
主要方法:
- 利用了来自226,459名参与者的英国生物库数据,随访时间中位数为13.7年.
- 评估轮班工作特征,生活方式因素 (体力活动,吸烟,饮食,睡眠,久坐时间,BMI,液体摄入量) 和石发病率.
- 采用Cox比例危险回归和调解分析来评估关联和调解效应.
主要成果:
- 轮班工作与结石事件的风险增加显著相关 (HR 1.15,95% CI 1.04-1.26).
- 这种关联在年轻的参与者 (<50岁) 和那些不从事重型手工劳动的人中更为强烈.
- 吸烟,睡眠时间,久坐时间,体重指数和水分摄入量成为显著的调解因素.
结论:
- 轮班工作是结石发展的独立风险因素.
- 生活方式因素部分解释了轮班工作和结石之间的联系.
- 促进健康生活方式的干预措施对于减轻轮班工人结石风险至关重要.
相关概念视频
01:27Urinary Tract Calculi IV: Nutrition Therapy and Prevention
354
Management of renal calculi focuses on effective strategies like tailored nutrition and hydration therapy. Adjusting diet and fluid intake reduces stone formation and recurrence, making these interventions simple yet powerful in kidney stone prevention and management.Understanding Kidney StonesKidney stones form when calcium, oxalate, uric acid, and cystine concentrate and crystallize in urine. Factors contributing to their formation include genetic predisposition, certain medical conditions,...
354
01:30Urinary Tract Calculi III: Medical Management
194
The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
194
01:28Urinary Tract Calculi V: Nursing Management
265
AssessmentSubjective Data: Obtain a detailed health history, including any recent or chronic urinary tract infections, periods of immobilization, previous episodes of renal calculi, and medical conditions such as gout, benign prostatic hyperplasia, or hyperparathyroidism. Review the medication history for drugs that may influence stone formation, including allopurinol, analgesics, loop diuretics, or thiazide diuretics. Document the use of long-term indwelling catheters and any past surgical...
265
01:28Urinary Tract Calculi I: Introduction
395
Renal calculi, or kidney stones, are solid deposits of minerals and salts formed inside the kidneys. In medical terminology, "calculus" refers to the stone itself, while "lithiasis" describes the process of stone formation. Depending on their location within the urinary system, these stones may be classified as either urolithiasis, when situated within the urinary tract, or nephrolithiasis, when located within the kidneys. Each term signifies the specific impact of the stone.Predisposition...
395
01:26Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
372
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
372
01:30Acute Kidney Injury IV: Diagnostic Studies and Prevention
260
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
260