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Updated: Aug 15, 2026

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在小鼠晚期怀孕期间胎儿器官发育的代谢景观

Chanyi Li1,2, Wuping Liu3, Xiaodong Li4

  • 1Stem Cell Research Center, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China.

Communications biology
|October 3, 2025
PubMed
概括

这项研究绘制了胎儿小鼠在孕期晚期器官的代谢发育图. 观察到关键的代谢变化,特别是脂肪酸和蛋白质消化,为出生后的生活做好了准备.

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Development of the Oral Microbiota01:28

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...