在牙恐惧症中,大脑的哪些区域更活跃:系统性审查
Mohammadreza Badi Sanaye1, Mahsa Moannaei2, Amir Mohammad Momeni1
1Student Research Committee, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
Odontology
|October 3, 2025
概括
这一系统性审查显示,牙恐惧与不同的大脑活动模式有关,特别是在额头和岛屿区域. 了解这些功能性大脑变化是开发针对牙科焦虑的向治疗的关键.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 医疗成像医学成像
背景情况:
- 牙恐惧症是一种影响个人的口腔健康的普遍情况.
- 功能性磁共振成像 (fMRI) 已被用于识别牙恐惧症期间活跃的大脑区域.
- 缺乏对牙科恐惧症的fMRI发现的全面概述.
研究的目的:
- 系统地审查和综合使用fMRI对患有牙恐惧症的个体中活跃大脑区域的证据.
- 提供牙科恐惧症的神经生物学相关的可靠概述.
主要方法:
- 在遵守PRISMA指南的基础上进行系统审查.
- 在多个数据库 (Web of Science,PubMed,Scopus,Embase,Ebsco) 和灰色文献中进行了搜索.
- 包括到2024年8月的研究,重点关注与对照组相比,患有牙恐惧症的个体的fMRI.
- 使用ROBINS-I V2工具评估偏差风险.
主要成果:
- 包括10篇文章,其中90%显示有中等偏差风险.
- 脑活动的显著差异观察到在额头区域,岛屿,皮下结构 (尾状核,皮体) 和头顶/后背皮层.
- 其他受影响的区域包括时,听觉,体感,运动区域和小脑.
结论:
- 牙科恐惧症与结构和功能性大脑变化有关.
- 考虑到性别差异和刺激反应的变化,可以加强对牙科恐惧症的个性化治疗策略.
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