相关实验视频

Updated: Jan 16, 2026

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
06:46

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Published on: September 27, 2024

643

PERK通路调节对结直肠癌管理的重要性:系统性审查

Marzieh Nemati1, Sanaz Dastghaib2,3, Zahra Hosseinzadeh2

  • 1Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.

BMC cancer
|October 3, 2025
PubMed
概括

结直肠癌中的蛋白质激酶RNA类内质网膜激酶 (PERK) 途径具有双重作用,有时抑制瘤生长,有时促进瘤生长. 了解这种上下文依赖的功能是开发有效的PERK向疗法的关键.

关键词:
结肠直肠癌是一种癌症.细胞内膜网膜应激压力是什么蛋白激酶RNA类似于内细胞网膜激酶.不折叠的蛋白质反应反应

更多相关视频

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies09:29

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies

Published on: September 30, 2016

14.3K
Using Human Differentially Expressed Gene Lists to Perform Downstream Pathway Enrichment Analysis and Target Prioritization03:08

Using Human Differentially Expressed Gene Lists to Perform Downstream Pathway Enrichment Analysis and Target Prioritization

Published on: October 3, 2025

900

相关概念视频

Interactions Between Signaling Pathways01:19

Interactions Between Signaling Pathways

Signaling cascades usually lack linearity. Multiple pathways interact and regulate one another, allowing cells to integrate and respond to diverse environmental stimuli.
Convergence and divergence, and cross-talk between signaling pathways
Two distinct signaling pathways can converge on a single functional unit, which may either be a single protein or a complex of proteins. The response is either functionally distinct or synergistic between the two pathways but different from the response...
7.2K
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
8.6K