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Updated: Jan 16, 2026

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骨髓介质干细胞衍生的外体细胞通过miR-223-3p介导的线粒细胞衰减肝星细胞激活

Lijie Ma1, Weidong Weng1, Jie Chen1

  • 1Department of Infectious Diseases, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang, 310000, China.

BMC medical genomics
|October 4, 2025
PubMed
概括

骨髓介质干细胞衍生的外体细胞 (BMSC外体细胞) 通过调节肝星细胞中的miR-223-3p来表现出抗纤维素作用. 这种机制涉及向HMGCS1和线粒细胞分裂,为肝纤维化提供潜在的新疗法.

关键词:
在BMSC-外基因组中.在HMGCS1中.肝脏纤维化 肝脏纤维化微型RNA-223-3p是什么意思线粒细胞衰变 (mitophagy) 是一种细胞衰变的过程.

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