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与疾病相关的miRNA突变与成熟miRNA的二次结构变化有关

Javor K Novev1, Sebastian E Ahnert2

  • 1Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom; Institute of Genetics and Cancer, The University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom.

Biophysical journal
|October 4, 2025
PubMed
概括

微RNA (miRNA) 的二次结构 (SS) 影响基因调节. 与疾病相关的miRNA突变往往导致改变的SS,突变者与野生类型相比,展开的概率更高.

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