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气候变暖和抗菌素耐药性之间的微生物相互作用威胁到土壤碳储存和全球健康

Shamik Roy^1,2, Marc G Dumont³, James A Bradley^4,5

¹School of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, United Kingdom.

The ISME journal

|October 4, 2025

概括

抗微生物耐药性 (AMR) 和气候变化可能会协同增加疾病风险和温室气体排放. 由于AMR而降低微生物碳使用效率可能会破坏土壤碳的稳定,特别是在快速变暖的北极地区.

科学领域:

环境科学环境科学
微生物学微生物学
气候变化研究气候变化研究

背景情况:

人类活动对环境产生影响,并可能产生复合效应.
气候变化和人类活动加快了抗菌素耐药性 (AMR) 在土壤生态系统中的传播.
快速变暖的北极地区拥有大量的土壤碳储量,容易受到环境变化的影响.

研究的目的:

研究抗微生物化合物和全球气温上升对气候变化和疾病风险的协同效应.
预测抗菌药物耐药性增加如何影响微生物碳利用效率 (CUE) 和随后的温室气体排放.
评估AMR通过改变微生物CUE影响土壤碳稳定性的潜力,特别是在北极地区.

主要方法:

概念建模和协同环境影响的预测.
在AMR增加的情况下,分析微生物资源分配.
评估微生物碳利用效率 (CUE) 的潜在变化.

主要成果:

预计抗菌化合物和气候变化具有协同效应,增强气候变化和疾病风险.
预计增加的AMR将通过将资源分配从生长转移到代谢和耐药性来减少微生物CUE.
降低CUE可能会导致温室气体释放增加,对土壤碳稳定性产生未知的影响.

结论:

抗微生物药物耐药性和气候变化之间的相互作用造成了严重的环境和健康问题.
由于AMR而改变的微生物CUE可能会影响全球碳循环,并加剧气候变化.
北极地区的独特脆弱性需要对抗药物耐药性和土壤碳稳定性给予紧急关注.

关键词:

抗微生物耐药性抗微生物耐药性碳使用效率的碳使用效率.气候变暖气候变暖微生物群落中的微生物群落.土壤生物地质化学土壤生物地质化学土壤碳土壤碳是什么

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