关于抗生素预防的SUFU最佳实践政策声明是否预测尿动力学研究后尿路感染? : 来自回顾性队列的证据
Omri Schwarztuch Gildor1,2, Elad Yosef1,2, Netanel Levin1,2
1Department of Urology, Meir Medical Center, 59 Tchernichovsky st, Kfar-Saba, 4428164, Israel.
World journal of urology
|October 4, 2025
概括
尿动力学研究 (UDS) 后的尿路感染 (UTI) 风险在目前的指导方针中并没有很好地预测. 水性,高后残留量 (PVR) 和神经性下尿路功能障碍 (NLUTD) 是后UDS尿路感染的关键预测因素.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 传染性疾病 传染性疾病
- 临床流行病学 临床流行病学
背景情况:
- 尿路感染 (UTI) 是尿动力学研究 (UDS) 后的潜在并发症.
- 根据泌尿动力学学会,女性盆腔医学和泌尿器官重建 (SUFU) 最佳实践政策声明 (BPPS),对于UDS后尿路感染的当前风险因素 (RF) 需要验证.
- 确定准确的预测因子对于优化抗生素预防和抗菌药物管理至关重要.
研究的目的:
- 为了验证SUFU BPPS RFs用于预测UDS后的UTI.
- 为了确定新的或更精确的RF,可以更好地指导抗生素预防决策.
- 在UDS的背景下,改善患者安全和抗菌药物管理.
主要方法:
- 对接受UDS的成年患者进行了回顾性队列研究.
- 作为主要终点,UDS在7天内进行培养确认的尿路感染.
- 回归分析以评估SUFU BPPS RFs和其他潜在预测因素,包括水,空虚后残留量 (PVR) 和神经性下尿路功能障碍 (NLUTD).
主要成果:
- 总共有1666名患者被纳入;1.9%的人患有尿路感染.
- 异常的生殖尿路 (GU) 解剖学是一个预测因素 (OR=3.26,p=0.033).
- 由于神经疾病导致的水性 (OR=4.98,p=0.004),PVR升高 (OR=2.80,p=0.011),以及NLUTD (OR=2.27,p=0.042) 是显著的预测因素. 在多变量分析中,高的PVR和NLUTD仍然是独立的预测因素.
结论:
- 根据SUFU BPPS标准,预测UDS后的尿路感染的准确性有限.
- 由于神经疾病而导致的水性,NLUTD和升高的PVR是后UDS尿路感染的显著预测因素.
- 将预防指南与这些已识别的RF更新,可以提高患者安全和抗菌药物管理.
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