亚裔美国人,夏威夷原住民和太平洋岛民患者的直肠癌手术和生存率
Kera L Kwan1, Carlos I Oronce2, Nicholas J Jackson3
1Department of Surgery, UCLA David Geffen School of Medicine, Los Angeles, California.
The Journal of surgical research
|October 4, 2025
概括
与其他亚洲亚组相比,夏威夷原住民和太平洋岛民 (NHPI) 患者在直肠癌治疗和生存率方面存在显著差异. 这些不平等现象,特别是关于关节保护手术 (SPS) 和死亡率,在高收入地区更为明显.
科学领域:
- 在瘤学瘤学.
- 医疗保健服务研究 医疗服务研究
- 健康差异 在健康上的差异
背景情况:
- 结直肠癌发病率的种族差异已经得到了充分的证据.
- 亚裔美国人,夏威夷原住民和太平洋岛民 (AANHPI) 患者经常被分组在一起,掩盖了关键的分组差异.
- 了解这些变异对于公平的癌症护理至关重要.
研究的目的:
- 检查不同AANHPI亚组中关节保护手术 (SPS) 率和生存率的变化.
- 为了确定特定的AANHPI亚群不成比例地受到直肠癌治疗和生存差异的影响.
- 调查社会经济因素对这些差异的影响.
主要方法:
- 对监测,流行病学和最终结果 (SEER) 数据 (2007-2021) 的回顾性分析.
- 包括经过手术的非转移性直肠腺癌患者.
- 种族分组定义为东亚人,夏威夷原住民和其他太平洋岛民 (NHPI),其他亚洲人,南亚人和东南亚人.
- 对于SPS赔率和Cox比例危险模型的整体生存的物流回归.
主要成果:
- 在7989名患者中,87.1%接受了SPS,总体5年生存率为81.4%.
- 与东亚患者相比,NHPI患者的SPS几率降低了42%,死亡风险增加了24%.
- 在居住在高收入县的NHPI患者中,差异最为明显,根据疾病阶段的变化.
结论:
- 在AANHPI亚组中,直肠癌治疗和生存率存在显著差异,NHPI患者面临最严重的差异.
- 高收入县的差距加剧表明需要探索结构性驱动因素.
- 有针对性的干预措施是必要的,以解决NHPI患者在癌症护理中的独特需求.
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