中国草药治疗焦虑症和强迫症:一个系统的综述与元分析
Yoann Birling1, Wing Yu Yu2, Rogier Hj Hoenders3
1NICM Health Research Institute, Western Sydney University, Locked Bag 1797, Penrith, NSW, 2751, Australia.
Journal of psychiatric research
|October 4, 2025
概括
中国草药 (CHM) 对泛性焦虑症 (GAD) 的治疗有前景,比抗焦虑药更有效,更安全. 对恐慌障碍和强迫症 (OCD) 需要进一步的研究.
科学领域:
- 综合医学是一个整体的医学.
- 精神病学是一个精神病学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 焦虑障碍和强迫症 (OCD) 是普遍存在的心理健康状况.
- 传统治疗包括抗焦虑药物,这些药物可能会产生副作用.
- 中国草药 (CHM) 越来越多地被探索其在心理健康中的治疗潜力.
研究的目的:
- 系统地审查CHM对焦虑症和强迫症的疗效和安全性.
- 为了将CHM与标准抗焦虑药物进行比较.
- 确定这些疾病的CHM治疗中的研究缺口.
主要方法:
- 对多个数据库 (EMBase,PubMed,CINAHL,CNKI,Wanfang,CQVIP,clinicaltrials.gov,中国临床试验注册) 进行了系统的搜索.
- 包含的研究是随机对照试验 (RCT),比较CHM与抗焦虑药物.
- 提取并分析了有效性 (减轻焦虑) 和安全性 (不良事件) 的数据.
主要成果:
- 与抗焦虑药物相比,CHM在一般性焦虑障碍 (GAD) (MD = -1.50,p < 0.001) 中在减少焦虑症状方面表现出更高的疗效.
- CHM的安全性显著提高,不良事件比抗焦虑药物少 (IRR = 0.33,p < 0.001).
- 缺乏高质量的证据支持对恐慌障碍和强迫症的CHM.
结论:
- 合并治疗对GAD具有有利的风险-益处概况,可以作为抗焦虑药物的替代品.
- 需要进一步的高质量的RCT来确定CHM对恐慌症,恐惧症和强迫症的有效性.
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