在勃起功能障碍患者中进行胺试验,以评估心血管风险
Andres Guillen Lozoya1, Mihai Dumbrava2, Milad Bonakdarhashemi1
1Department of Urology, Mayo Clinic Rochester, Rochester, Minnesota, 55905, United States.
The journal of sexual medicine
|October 5, 2025
概括
血清胺测试可能有助于确定勃起功能障碍 (ED) 的男性心血管风险. 异常的胺水平与ED严重程度有关,这表明对心脏转诊的潜在益处.
科学领域:
- 心血管健康 心血管健康
- 内分泌学 在内分泌学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 勃起功能障碍 (ED) 与心血管疾病 (CVD) 密切相关,往往是之前或伴随着它.
- 勃起障碍的严重程度可以预测心血管疾病的严重程度.
研究的目的:
- 调查诊断为ED的患者测量血清胺水平的临床实用性.
- 为了确定异常的胺水平是否与ED严重程度和心血管风险升高相关.
主要方法:
- 从ED患者的电子健康记录中回顾血清胺水平的分析.
- 基于ED严重程度的患者分层使用国际勃起功能指数 (IIEF) 的勃起功能领域.
主要成果:
- 在审查的354名患者中,71.5%出现中度至重度的ED.
- 在异常的amid值和中度至重度的ED症状之间发现了统计学上显著的关联.
- 仅基于IIEF评分的ED严重程度,增加了异常胺测试的几率 (OR2.3,P=.034).
结论:
- 血清胺测试显示,它有可能成为识别ED男性心血管风险的有价值工具.
- 在ED患者中异常的胺水平可能需要进一步的心脏评估和改变生活方式的建议.
- 将血清胺测试纳入ED管理中可以促进及时的心脏转诊.
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