基于氨基酸和米配方的味道问题在牛奶过敏中的牛奶过敏
1Department of Pediatric Allergy and Immunology, Manisa City Hospital, Manisa, Turkey.
Clinical pediatrics
|October 5, 2025
概括
患有牛奶蛋白过敏 (CMPA) 的婴儿通常会因为口味不佳而拒绝特殊配方. 这项研究发现,大约一半的婴儿拒绝了这些配方,强调口味是管理CMPA的重要障碍.
科学领域:
- 儿科过敏和免疫学
- 临床营养学 临床营养学
- 胃肠病学 胃肠病学
背景情况:
- 牛奶蛋白过敏 (CMPA) 需要无乳制品饮食,通常涉及专门的婴儿配方奶粉.
- 基于氨基酸和基于大米的配方是常见的替代品,但经常面临可口性问题.
- 由于口味而拒绝配方是管理CMPA的一个重大挑战,影响营养支持.
研究的目的:
- 在被诊断患有CMPA的婴儿中,评估基于氨基酸或基于米的配方的可口性和可接受性.
- 确定婴儿在最初的7天内接受处方配方奶粉的比例.
- 确定影响婴儿接受CMPA配方的因素.
主要方法:
- 追溯横截面研究涉及102名婴儿,诊断出IgE介导或非IgE介导的CMPA.
- 婴儿接受了无牛奶饮食,并补充了基于特定氨基酸 (Neocate Numil,Aptamil Pregomin-Numil,Alfamino-Nestlé) 或基于大米 (Evolvia RP-Montero) 的配方.
- 主要结果:接受7天内处方奶粉的婴儿比例;影响因素的二次分析.
主要成果:
- 总体而言,47.1%的初次配方使用者接受了处方配方,在转换后增加到50%.
- 根据性别,年龄,过敏类型 (IgE介导与非IgE介导) 或母乳养状态,没有发现配方接受度的显著差异.
- 大约一半的被研究的婴儿拒绝了专用配方,这表明口感不佳是一个持久的问题.
结论:
- 可口味性仍然是用于管理CMPA的氨基酸和米配方的主要挑战.
- 很大一部分婴儿拒绝这些必要的配方,强调了需要改善口味的替代品.
- 临床和人口因素没有显著预测配方接受,强调口味障碍的普遍性.
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