过敏性鼻炎,喘和喉回流性疾病之间的相关性:系统性审查
Baraa Ibrahim Awad1, Laila Salah Aldokhail2, Enar Mohammed Alotaibi2
1Department of Otolaryngology-Head & Neck Surgery, College of Medicine, King Abdullah International Medical Research Center, King Saud bin Abdulaziz University for Health Sciences, Ministry of the National Guard Health Affairs, Jeddah, Saudi Arabia.
喉回流 (LPR) 与过敏性鼻炎 (AR) 和喘有关. 管理这些相互连接的气道状况可能会改善患者的治疗结果.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 肺部病理学 肺部病理学
- 过敏和免疫学 过敏和免疫学
背景情况:
- 喉回流 (LPR),过敏性鼻炎 (AR) 和喘是共享炎症通路的常见呼吸道疾病.
- 这是一个很棒的节目,这是一个很棒的节目.
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- 假设链接AR和喘,而LPR在他们的恶化中的作用正在调查中.
- 了解这些相互作用对于改善临床管理至关重要.
研究的目的:
- 系统地审查和评估LPR,AR和喘之间的联系.
- 分析那些在不同患者群体中检查这些并发症的研究.
主要方法:
- 在PubMed,Scopus和Google Scholar中进行了全面的系统文献搜索,直到2024年.
- 研究是根据预先定义的标准进行选择的,提取了有关患病率,诊断和条件间关联的数据.
- 该审查已与PROSPERO (CRD42024588367) 注册,并包括对协会的统计分析.
主要成果:
- 在LPR和AR之间发现了显著的正相关性,症状严重程度与LPR严重程度相关.
- 在LPR和喘之间观察到强烈的关联,特别是在控制不良的情况下.
- 抗肺炎和喘之间的强有力的关系支持"联合呼吸道"假设,表明共享的炎症.
结论:
- 这次审查证实了LPR,AR和喘之间的显著关联,突出了它们作为并发症的重要性.
- 识别和管理这些相互关联的疾病对于有效的临床实践至关重要.
- 对诊断和治疗的多学科方法可以通过解决这些呼吸道疾病之间的相互作用来改善结果.
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