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Updated: Jan 16, 2026

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
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用随机生存森林为孤儿药物产品首次提交仿制药申请的预测分析

Robert Hopefl1, Jing Wang1, Abhinav Ram Mohan1

  • 1Division of Quantitative Methods and Modeling, Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.

Clinical and translational science
|October 5, 2025
PubMed
概括

开发通用孤儿药物 (ODP) 可以降低罕见病患者的成本. 这项研究确定了影响通用ODPs缩写新药应用 (ANDAs) 的关键因素,使用机器学习预测提交并为增加可用性的策略提供信息.

关键词:
仿制药是一般的药物.机器学习是机器学习.孤儿药物是一种孤儿药物.时间到事件分析分析.

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