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Updated: Sep 30, 2026

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在患有原发性胆道胆炎的患者中,血液循环中的T毛囊辅助细胞和T外围辅助细胞子集的剖析

Haixia Ma1, Ying Liu2, Yuehong Zhu3

  • 1Department of Key Laboratory, The Affiliated Changshu Clinical College of Xuzhou Medical University, Changshu 215500, China.

Immunology letters
|October 5, 2025
PubMed
概括

在初级胆道胆炎 (PBC) 患者中,T毛囊辅助细胞 (Tfh) 和外围T辅助细胞 (Tph) 的水平升高. 这些免疫细胞有潜力成为诊断PBC和评估疾病严重程度的生物标志物.

关键词:
原发性胆道胆管炎是一种胆道胆管炎.在T毛囊辅助细胞中.周围的T辅助细胞

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When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...