肝移植后的慢性疼痛:一个横截面研究
A Duarte1, F Farias1, V Pires1
1Department of Anaesthesiology, Unidade Local de Saúde São José, Lisbon, Portugal.
Revista espanola de anestesiologia y reanimacion
|October 5, 2025
概括
慢性术后疼痛 (CPSP) 影响了20%的肝移植接受者,特别是女性. 解决急性术后疼痛对于预防CPSP和改善患者的治疗结果至关重要.
科学领域:
- 疼痛管理 疼痛管理
- 移植手术 移植手术
- 患者的治疗结果.
背景情况:
- 慢性术后疼痛 (CPSP) 是肝移植后的一个重要且研究不足的并发症.
- 尽管取得了进展,但CPSP的患病率仍然是移植受体的担忧.
研究的目的:
- 确定肝移植患者中CPSP的患病率和特征.
- 识别与CPSP发展相关的风险因素.
- 评估CPSP对患者日常生活和当前治疗状态的影响.
主要方法:
- 一项涉及310名肝移植患者 (2017年1月至2021年12月) 的横截面回顾性研究.
- 通过电话问卷 (简要疼痛清单简短表格,DN4) 和临床病史审查收集的数据.
- 统计分析以确定CPSP的预测因素和患病率.
主要成果:
- CPSP的患病率为20.0%,女性 (27.6%) 和男性 (17.0%) 的患病率更高.
- 急性术后疼痛和女性性别是CPSP的显著独立预测因素.
- 神经病痛特征在25.8%的CPSP病例中被发现,显著影响日常活动;只有24.2%接受治疗.
结论:
- CPSP显著影响肝移植接受者,需要改进疼痛管理策略.
- 解决急性术后疼痛对于预防CPSP至关重要.
- 需要提高意识和治疗方案,以改善患有CPSP的肝移植患者的治疗结果.
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