相关实验视频

Updated: Jan 16, 2026

Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
10:58

Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules

Published on: July 25, 2013

17.6K

在合理的金属酶设计中的计算工具

Mohd Taher1, Shyamalava Mazumdar1

  • 1Department of Chemical Sciences, Tata Institute of Fundamental Research, Mumbai, India.

Methods in enzymology
|October 5, 2025
PubMed
概括

计算式酶设计扩大了金属酶合成细化学物质的能力. 这种方法使用细胞P450作为模型,增强了对新基质的酶选择性.

关键词:
生物催化剂是一种生物催化剂.计算式酶设计的计算方法分子对接是分子对接.多个序列对齐的调整.蛋白质工程是一种蛋白质工程.有理性的酶设计.

更多相关视频

Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins05:08

Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins

Published on: July 8, 2025

943
Author Spotlight: In Silico Creation and Impact of Carbonylated Amino Acids on Protein Structure and Function05:57

Author Spotlight: In Silico Creation and Impact of Carbonylated Amino Acids on Protein Structure and Function

Published on: April 26, 2024

833

相关概念视频

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving01:29

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving

Mechanistic models play a crucial role in algorithms for numerical problem-solving, particularly in nonlinear mixed effects modeling (NMEM). These models aim to minimize specific objective functions by evaluating various parameter estimates, leading to the development of systematic algorithms. In some cases, linearization techniques approximate the model using linear equations.
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
288