手术前的抗吸收药物是否会影响整个关节置换的结果?
Mahdi Zakeri1, Jordan Manley2, Patrick Louis3
1Department of Oral & Maxillofacial Surgery, Orthognathic and Temporomandibular Joint Surgery, University of Alabama at Birmingham, Birmingham, AL, USA.
手术前的抗吸收疗法对接受关节全关节置换 (TJR) 的骨质疏松患者是安全的,没有增加并发症风险或对功能结果产生负面影响.
科学领域:
- 口腔和牙面部外科手术
- 整形外科手术 整形外科手术
- 类风湿病学 类风湿病学
背景情况:
- 骨质疏松症的管理通常涉及抗吸收疗法.
- 关节全关节置换 (TJR) 是一种治疗晚期关节疾病的方法.
- 抗吸收疗法对骨质疏松患者TJR结果的影响尚未得到充分证实.
研究的目的:
- 评估关节TJR在接受抗吸收疗法的骨质疏松患者的临床和放射性结果.
- 在这个特定的患者群体中评估TMJ TJR的安全性和有效性.
主要方法:
- 对接受TMJ TJR的骨质疏松患者的回顾性图表审查.
- 数据收集包括人口统计,抗吸收疗法细节,手术信息和术后结果.
- 临床评估运动范围 (ROM) 和关节噪声;对周围假肢骨和植入物稳定性的放射性评估.
主要成果:
- 分析了8名骨质疏松症患者,他们之前接受过抗吸收疗法.
- 没有出现与药物相关的骨 (MRONJ),假肢失败或植入物松动的病例.
- 观察到有利的功能结果,平均术后ROM为35.1毫米,没有关节噪声.
结论:
- 手术前的抗吸收疗法似乎不会影响骨质疏松症患者的TMJ TJR结果.
- 需要进一步的多中心研究来确认使用更大的样本大小的安全性和有效性.
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