身体形状指数改变了空气污染和心脏代谢多病症之间的关联
Zhao-Wei Wang1, Chengwu Hu1, Bo Zhou2
1Department of Neurology, Qianjiang Central Hospital of Hubei Province, Hubei, China.
Scientific reports
|October 5, 2025
概括
空气污染增加了心脏代谢多病症 (CMM) 的风险,特别是在具有较高A体形指数 (ABSI) 的个体中,这表明腹部肥胖. 这凸显了身体形状如何放大环境健康风险,建议采取综合预防策略.
科学领域:
- 环境健康 环境健康
- 流行病学 流行病学
- 代谢性疾病研究研究
背景情况:
- 长期暴露于空气污染与心脏代谢疾病有关.
- 身体形状分布,特别是腹部脂肪度对这种关联的影响还不太清楚.
- 调查身体形状指数 (ABSI) 作为修饰因素对于了解个性化健康风险至关重要.
研究的目的:
- 检查身体形状指数 (ABSI) 是否改变了空气污染暴露和心脏代谢多病症 (CMM) 之间的关系.
- 评估各种空气污染物 (PM2.5,PM10,PM1,SO2,NO2,O3) 对中国成年人的CMM的影响.
- 为了确定针对性公共卫生干预的高风险人群.
主要方法:
- 利用来自查尔斯第3波 (2015) 的10,487名中年和老年中国成年人 (≥45岁) 的数据.
- 使用卫星模型计算ABSI并评估个人空气污染物暴露.
- 使用通用线性模型与相互作用术语来分析关联和修改效应.
主要成果:
- 所有六种测量的空气污染物 (PM2.5,PM10,PM1,SO2,NO2,O3) 都与CMM患病率的增加显著相关.
- 更高的ABSI独立地与更高的CMM风险有关.
- 观察到ABSI和所有空气污染物之间的显著相互作用,在ABSI最高的个体中,污染-CMM关联更强.
结论:
- 身体形状指数显著改变了中国老年人空气污染和心脏代谢多病症之间的关联.
- 腹部脂肪 (以高的ABSI表示) 加剧了空气污染暴露的健康风险.
- 调查结果强调了需要综合战略,解决空气质量和肥胖管理,以预防心脏代谢疾病.
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