修饰性硬化结合与带结合治疗II/III级出血疾病:一项回顾性研究
Wei Wang1,2, Yupeng Zheng1,2, Jun Lu1,2
1Department of Colorectal and Anal Surgery, Ningbo Medical Centre LiHuiLi Hospital, 1111 Jiangnan Road, Ningbo, 315000, People's Republic of China.
International journal of colorectal disease
|October 5, 2025
概括
修改后的硬化结合手术有效治疗病,失败和出血率较低. 这种结合带绑定和聚多卡诺尔泡硬化疗法的结合方法提供了更安全,更有效的治疗选择.
科学领域:
- 胃肠病学和外科创新.
- 对直肠疾病进行最少的侵入性治疗.
背景情况:
- 出血疾病 (HD) 影响了人口的很大一部分.
- 传统的带绑定 (RBL) 是一种常见的治疗方法,但具有局限性.
- 需要提高治疗的有效性和安全性.
研究的目的:
- 评估修饰性硬化包裹 (mSB) 程序对II/III级病的疗效和安全性.
- mSB手术结合了带绑定 (RBL) 和3%的聚多卡诺尔泡硬化疗法 (PFS).
主要方法:
- 追溯性研究比较mSB与传统RBL在307名II/III级HD.患者中.
- 主要结局:治疗失败率和延迟大量出血 (DMB).
- 二级结局:术后并发症,症状评分 (HDSS,SHS-HD) 和患者满意度 (PS).
主要成果:
- 与RBL组 (125名患者) 相比,mSB组 (162名患者) 的复发率 (6.8%vs17.0%) 和治疗失败率 (6.8%vs18.6%) 显著降低.
- 在mSB组中没有出现延迟大量出血的病例,而在RBL组中只有5例.
- 手术后的并发症是相似的,在mSB组的第七天发现出血有所改善.
结论:
- 修改硬质结合手术是一种安全有效的治疗II/III级出血疾病的方法.
- mSB减少了绑定疗程,降低了延迟出血的风险,并降低了治疗失败率.
- 这种创新方法提供了与传统RBL相比的术后并发症概况.
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