2017年至2024年,英国伦敦的艾滋病毒预防:成果,差距和经验教训
Gary Whitlock1,2, Stephen Cole1, Afshan Khurshid1
1Chelsea and Westminster Hospital, London, UK.
HIV medicine
|October 6, 2025
概括
伦敦性健康诊所56迪恩街的艾滋病毒诊断在2017年至2024年期间下降了61%,暴露前预防 (PrEP) 使用量显著增加. 尽管取得了成功,但艾滋病毒预防方面的差距仍然存在,这质疑了2030年零传播目标.
科学领域:
- 性健康 性的健康
- 传染病流行病学 传染病流行病学
- 公共卫生干预措施 公共卫生干预措施
背景情况:
- 自2017年以来,伦敦迪恩街56号 (56DS) 的艾滋病毒诊断数量一直在下降.
- 了解艾滋病毒预防策略的演变和影响对于公共卫生工作至关重要.
研究的目的:
- 描述2017年至2024年期间56DS的艾滋病毒预防策略的演变.
- 评估这些策略对新的艾滋病毒诊断的影响.
- 发现艾滋病毒预防的现有缺口.
主要方法:
- 2017年1月至2024年12月利用常规临床编码数据进行艾滋病毒检测,诊断和治疗.
- 经过审查的患者笔记,以查看被诊断患有艾滋病毒的个体的特征和开始抗逆转录病毒治疗 (ART) 的时间.
- 收集关于暴露前预防 (PrEP) 和暴露后预防 (PEPSE) 使用的数据.
主要成果:
- 新的艾滋病毒诊断减少了61% (2017年为209例,到2024年为82例).
- 准备剂使用者显著增加,从2017年第一季度的170人增加到2023年第二季度的25149人.
- 开始ART的中位时间保持稳定,为7天.
结论:
- 56DS HIV 组合预防模型仍然有效,关键人群中的 HIV 诊断率下降.
- 观察到PrEP摄入量大幅增加.
- 鉴定到的预防差距引发了人们对到2030年实现零艾滋病毒传播的担忧.
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