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Updated: Jan 16, 2026

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通过全息加热显微镜的时空温度控制揭示了细胞热敏信号

Kotaro Oyama1, Ayumi Ishii2, Shuhei Matsumura2

  • 1Takasaki Institute for Advanced Quantum Science, National Institutes for Quantum Science and Technology, 1233 Watanukimachi, Takasaki, Gunma 370-1292, Japan. oyama.kotaro@qst.go.jp.

Lab on a chip
|October 6, 2025
PubMed
概括

全息加热显微镜精确控制温度,可视化细胞反应. 这项新技术揭示了细胞如何感知和信号温度变化,使细胞功能能够进行热操纵.

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Thermosensation01:43

Thermosensation

Peripheral thermosensation is the perception of external temperature. A change in temperature (on the surface of the skin and other tissues) is detected by a family of temperature-sensitive ion channels called Transient Receptor Potential, or TRP, receptors. These receptors are located on free nerve endings. Those detecting cold temperatures are closer to the surface of the skin than the nerve endings detecting warmth. These thermoTRP channels, while temperature selective, have relatively...
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